We may be moving towards an era where nurses may get what they say they have always wanted – totally personalized care. This paper examines four major trends, i.e. the increasing importance of the genome, the informed patient, the rise of the patient-payer, and the 'instant gratification generation'. Each individually, and in combination, will have potential impacts on the future of health and nursing. The implications of these issues, and others are explored, as well as nursing's readiness to deal with the implications of truly and totally personalized care.
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