Dry eye syndrome is a common disorder of the tear film, affecting a significant percentage of the population. The Break-Up Time (BUT) is a clinical test used for the diagnosis of this disease. In this work, we propose several improvements for the automatic computation of the BUT measure that solve the limitations of previous approaches. In particular, we present several procedures for the automatic computation of some parameters involved in the BUT measurement, such as the eye size, the intensity variation, or the starting point of the measurement frame sequence. We have tested our methodology on a dataset composed of 18 videos annotated by 4 different experts. The average difference between the automatic measure and the experts’ measures is on the acceptable range considering the high inter-observer variance.
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