Learning is no longer an internal individual activity but occurs through networks and connections. The aim of this project was to teach online health informatics students to use Web 2.0 tools and technologies to form networks and connections through experiential learning assignments. Web 2.0 tools and technologies were evaluated using a criteria checklist prior to implementation for students enrolled in health informatics classes at the University of Kansas School of Nursing. Health informatics students have developed competencies using an instant message service, blogging, concept mapping, social bookmarking, and interacting a virtual environment. In the future, health care professionals will have to work in rapidly changing environments and keep abreast of new innovations and tools, learn to use those tools, and to teach others about the tools.