To keep healthcare effective, accessible and affordable to all we need a fundamental paradigm shift. Self-management for prevention and care with the help of healthcare professionals, having a shared view of the state of well-being, will play a significant role in this transition. The problem list is widely adopted as centerpiece of electronic health records and is although often patient oriented, but mostly limited to the institutional level. The requirements for this paradigm shift has been discussed in a series of workshops. Truly person-centered care requires to move towards a holistic problem list with an assessment and planning process resulting in an overarching care plan. The change process towards a real person-centered problem list, integrated in an overarching care plan, should be focused on the transition of health services delivery and requires a transition based on the “Quadruple Aim” principles.